Two sample MR report
Triacylglycerol (54:6) levels against Malignant_melanoma_of_skin
Date: 04 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.4977067 | 0.2611541 | 0.3076296 |
| Weighted median | 3 | 0.2527336 | 0.1050905 | 0.0161763 |
| Inverse variance weighted | 3 | 0.2594688 | 0.0892293 | 0.0036388 |
| Simple mode | 3 | 0.1728115 | 0.1353486 | 0.3298772 |
| Weighted mode | 3 | 0.3218628 | 0.1206988 | 0.1165482 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0069098 | 1 | 0.9337519 |
| Inverse variance weighted | 0.9491018 | 2 | 0.6221644 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0349003 | 0.035955 | 0.5094757 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002081 | 0 | TRUE | 0.2439108 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
