Two sample MR report
Triacylglycerol (58:7) levels against Malignant_melanoma_of_skin
Date: 04 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.4986779 | 0.2481104 | 0.1148117 |
| Weighted median | 6 | 0.1095196 | 0.0829244 | 0.1865962 |
| Inverse variance weighted | 6 | 0.1378883 | 0.0659283 | 0.0364842 |
| Simple mode | 6 | 0.1100761 | 0.1255608 | 0.4207800 |
| Weighted mode | 6 | 0.1040869 | 0.1197112 | 0.4243473 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.662729 | 4 | 0.4535700 |
| Inverse variance weighted | 5.911579 | 5 | 0.3149179 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0556397 | 0.0371026 | 0.2080942 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004493 | 0 | TRUE | 0.1306094 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
