Two sample MR report
Uridine against Malignant_melanoma_of_skin
Date: 03 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -1.672078 | 5.556999 | 0.8139297 |
| Weighted median | 3 | 1.900548 | 1.412723 | 0.1785256 |
| Inverse variance weighted | 3 | 2.908749 | 1.147536 | 0.0112519 |
| Simple mode | 3 | 1.900955 | 1.790950 | 0.3997239 |
| Weighted mode | 3 | 1.900955 | 1.599919 | 0.3567388 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.9329153 | 1 | 0.3341065 |
| Inverse variance weighted | 1.6427112 | 2 | 0.4398350 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0517559 | 0.0614318 | 0.5542896 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001137 | 0 | TRUE | 0.3804024 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
