Two sample MR report
Triglycerides in small VLDL against Malignant_melanoma_of_skin
Date: 03 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 13 | 0.1102129 | 0.1664854 | 0.5216000 |
| Weighted median | 13 | 0.2537618 | 0.0817546 | 0.0019096 |
| Inverse variance weighted | 13 | 0.1700062 | 0.0628484 | 0.0068300 |
| Simple mode | 13 | 0.2860390 | 0.1640196 | 0.1067068 |
| Weighted mode | 13 | 0.2891287 | 0.1069652 | 0.0192019 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 14.27801 | 11 | 0.2179900 |
| Inverse variance weighted | 14.47576 | 12 | 0.2713638 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0078737 | 0.0201723 | 0.7037521 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.000302 | 0 | TRUE | 0.0227706 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
