Two sample MR report
Triglycerides in very small VLDL against Malignant_melanoma_of_skin
Date: 03 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 19 | 0.2788532 | 0.1384577 | 0.0601153 |
| Weighted median | 19 | 0.1459655 | 0.0727807 | 0.0449041 |
| Inverse variance weighted | 19 | 0.1063337 | 0.0495572 | 0.0318987 |
| Simple mode | 19 | 0.1441387 | 0.1304909 | 0.2838853 |
| Weighted mode | 19 | 0.2086070 | 0.1258384 | 0.1146958 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 12.91056 | 17 | 0.7421527 |
| Inverse variance weighted | 14.69121 | 18 | 0.6830490 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0220787 | 0.0165457 | 0.1996685 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003487 | 0 | TRUE | 0.018217 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
