Two sample MR report
N-acetylcarnosine levels against Malignant_melanoma_of_skin
Date: 03 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0964372 | 0.2348844 | 0.7089489 |
| Weighted median | 5 | -0.0823490 | 0.0761800 | 0.2797067 |
| Inverse variance weighted | 5 | -0.1409581 | 0.0656154 | 0.0316941 |
| Simple mode | 5 | -0.0585090 | 0.1129962 | 0.6319206 |
| Weighted mode | 5 | -0.0631131 | 0.0858225 | 0.5028922 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.312788 | 3 | 0.3458667 |
| Inverse variance weighted | 4.533606 | 4 | 0.3385813 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0409231 | 0.0389206 | 0.3702696 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0019405 | 0 | TRUE | 0.000124 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
