Two sample MR report
1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1) levels against Malignant_melanoma_of_skin
Date: 03 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | -0.1329878 | 0.0950337 | 0.2342737 |
| Weighted median | 6 | -0.1184701 | 0.0546148 | 0.0300680 |
| Inverse variance weighted | 6 | -0.1122484 | 0.0478605 | 0.0190105 |
| Simple mode | 6 | -0.1302560 | 0.0883585 | 0.2004387 |
| Weighted mode | 6 | -0.1208507 | 0.0597541 | 0.0990581 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.365827 | 4 | 0.6688115 |
| Inverse variance weighted | 2.429636 | 5 | 0.7870527 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0042388 | 0.0167804 | 0.8130237 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.003769 | 0 | TRUE | 1e-07 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
