Two sample MR report
1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0) levels against Malignant_melanoma_of_skin
Date: 03 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | -0.0767249 | 0.0963144 | 0.4618101 |
| Weighted median | 7 | -0.1058378 | 0.0498614 | 0.0337841 |
| Inverse variance weighted | 7 | -0.0869196 | 0.0430995 | 0.0437246 |
| Simple mode | 7 | -0.0826488 | 0.0802120 | 0.3425650 |
| Weighted mode | 7 | -0.1048059 | 0.0518462 | 0.0897167 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 6.319170 | 5 | 0.2763892 |
| Inverse variance weighted | 6.337791 | 6 | 0.3864331 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0021303 | 0.0175501 | 0.908115 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0044801 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
