Two sample MR report
Hypotaurine to taurine ratio against Malignant_melanoma_of_skin
Date: 03 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 1.6627588 | 1.2693220 | 0.4150834 |
| Weighted median | 3 | -0.3551585 | 0.1518561 | 0.0193467 |
| Inverse variance weighted | 3 | -0.2902188 | 0.1421119 | 0.0411332 |
| Simple mode | 3 | -0.4558546 | 0.2318496 | 0.1881867 |
| Weighted mode | 3 | -0.4547954 | 0.2430952 | 0.2022722 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.2170201 | 1 | 0.6413199 |
| Inverse variance weighted | 2.6072899 | 2 | 0.2715402 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1763924 | 0.1140923 | 0.365502 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.93e-05 | 0 | TRUE | 0.5067306 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
