Two sample MR report
Omega-3 fatty acids || id:met-d-Omega_3 against Cardiovascular disease || id:ebi-a-GCST90086053
Date: 20 December, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 74 | 0.108 | 0.078 | 0.172 |
| Weighted median | 74 | 0.109 | 0.070 | 0.119 |
| Inverse variance weighted | 74 | 0.106 | 0.057 | 0.064 |
| Simple mode | 74 | 0.310 | 0.163 | 0.061 |
| Weighted mode | 74 | 0.145 | 0.057 | 0.013 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 96.7 | 72 | 0.028 |
| Inverse variance weighted | 96.7 | 73 | 0.033 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0 | 0.005 | 0.961 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.003 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
