Two sample MR report
FA against PRKAB1-UKBPPP
Date: 08 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | -0.005 | 0.041 | 0.910 |
| Weighted median | 7 | -0.015 | 0.013 | 0.241 |
| Inverse variance weighted | 7 | -0.018 | 0.010 | 0.085 |
| Simple mode | 7 | -0.005 | 0.020 | 0.800 |
| Weighted mode | 7 | -0.012 | 0.017 | 0.500 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 6.04 | 5 | 0.302 |
| Inverse variance weighted | 6.17 | 6 | 0.404 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.004 | 0.013 | 0.756 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.408 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
