Two sample MR report
UKB-b-10817 against ukb-a-115
Date: 23 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 57 | -0.002 | 0.001 | 0.141 |
| Weighted median | 57 | 0.000 | 0.001 | 0.525 |
| Inverse variance weighted | 57 | -0.001 | 0.001 | 0.009 |
| Simple mode | 57 | 0.001 | 0.002 | 0.613 |
| Weighted mode | 57 | 0.001 | 0.002 | 0.643 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 51.4 | 55 | 0.613 |
| Inverse variance weighted | 51.7 | 56 | 0.638 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0 | 0 | 0.576 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.618 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
