Two sample MR report
UKB-b-12963 against finn-b-L12_ATOPIC
Date: 22 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 23 | 0.349 | 0.368 | 0.354 |
| Weighted median | 23 | 0.368 | 0.352 | 0.296 |
| Inverse variance weighted | 23 | 0.310 | 0.257 | 0.228 |
| Simple mode | 23 | -0.792 | 0.846 | 0.359 |
| Weighted mode | 23 | 0.350 | 0.357 | 0.337 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 17.9 | 21 | 0.653 |
| Inverse variance weighted | 18.0 | 22 | 0.709 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.001 | 0.01 | 0.885 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.816 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
