Two sample MR report
UKB-b-12963 against finn-b-L12_VITILIGO
Date: 23 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 23 | 4.61 | 2.52 | 0.081 |
| Weighted median | 23 | 4.61 | 2.52 | 0.067 |
| Inverse variance weighted | 23 | 4.22 | 1.76 | 0.016 |
| Simple mode | 23 | 1.12 | 5.24 | 0.833 |
| Weighted mode | 23 | 4.54 | 2.53 | 0.087 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 15.6 | 21 | 0.790 |
| Inverse variance weighted | 15.7 | 22 | 0.831 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.014 | 0.067 | 0.831 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.815 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
