Two sample MR report
UKB-b-9942 against finn-b-L12_HIDRADENITISSUP
Date: 22 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 593 | 0.514 | 0.539 | 0.341 |
| Weighted median | 593 | 0.966 | 0.541 | 0.074 |
| Inverse variance weighted | 593 | 0.517 | 0.298 | 0.083 |
| Simple mode | 593 | -0.452 | 1.373 | 0.742 |
| Weighted mode | 593 | 1.078 | 0.775 | 0.165 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 546 | 591 | 0.906 |
| Inverse variance weighted | 546 | 592 | 0.911 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0 | 0.008 | 0.994 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.385 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
