Two sample MR report
ABHD12_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0162800 | 0.1971803 | 0.9417176 |
| Weighted median | 4 | -0.0245149 | 0.0135901 | 0.0712509 |
| Inverse variance weighted | 4 | -0.0254597 | 0.0110608 | 0.0213469 |
| Simple mode | 4 | -0.0233466 | 0.0175354 | 0.2751857 |
| Weighted mode | 4 | -0.0228317 | 0.0183929 | 0.3026971 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.7636691 | 2 | 0.6826080 |
| Inverse variance weighted | 0.7658433 | 3 | 0.8576182 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0049469 | 0.1060932 | 0.9670469 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.4e-05 | 0 | TRUE | 0.5297942 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
