Two sample MR report
ABO_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method |
nsnp |
b |
se |
pval |
| MR Egger |
5 |
0.0217698 |
0.1328499 |
0.8802531 |
| Weighted median |
5 |
-0.0405392 |
0.0132545 |
0.0022244 |
| Inverse variance weighted |
5 |
-0.0338732 |
0.0125047 |
0.0067521 |
| Simple mode |
5 |
-0.0507107 |
0.0228040 |
0.0902343 |
| Weighted mode |
5 |
-0.0498836 |
0.0244214 |
0.1106141 |
Heterogeneity tests
| method |
Q |
Q_df |
Q_pval |
| MR Egger |
5.954466 |
3 |
0.1138467 |
| Inverse variance weighted |
6.306586 |
4 |
0.1773923 |
Test for directional horizontal pleiotropy
| egger_intercept |
se |
pval |
| -0.0516666 |
0.1226662 |
0.7019676 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure |
snp_r2.outcome |
correct_causal_direction |
steiger_pval |
| 8.06e-05 |
0 |
TRUE |
0.3975582 |
Note - R^2 values are approximate
Forest plot of single SNP MR

Comparison of results using different MR methods

Funnel plot

Leave-one-out sensitivity analysis
