Two sample MR report


ABO_Epithelial against bbj-a-88

Date: 13 January, 2026


Results from two sample MR:

method nsnp b se pval
MR Egger 5 0.0217698 0.1328499 0.8802531
Weighted median 5 -0.0405392 0.0132545 0.0022244
Inverse variance weighted 5 -0.0338732 0.0125047 0.0067521
Simple mode 5 -0.0507107 0.0228040 0.0902343
Weighted mode 5 -0.0498836 0.0244214 0.1106141

Heterogeneity tests

method Q Q_df Q_pval
MR Egger 5.954466 3 0.1138467
Inverse variance weighted 6.306586 4 0.1773923

Test for directional horizontal pleiotropy

egger_intercept se pval
-0.0516666 0.1226662 0.7019676

Test that the exposure is upstream of the outcome

snp_r2.exposure snp_r2.outcome correct_causal_direction steiger_pval
8.06e-05 0 TRUE 0.3975582

Note - R^2 values are approximate


Forest plot of single SNP MR

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Comparison of results using different MR methods

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Funnel plot

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Leave-one-out sensitivity analysis

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