Two sample MR report
ADK_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.0019376 | 0.4126490 | 0.9966797 |
| Weighted median | 4 | 0.0366466 | 0.0196696 | 0.0624466 |
| Inverse variance weighted | 4 | 0.0367466 | 0.0172251 | 0.0328993 |
| Simple mode | 4 | 0.0365035 | 0.0269456 | 0.2685019 |
| Weighted mode | 4 | 0.0360771 | 0.0261678 | 0.2618097 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0031977 | 2 | 0.9984024 |
| Inverse variance weighted | 0.0103258 | 3 | 0.9997218 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0166298 | 0.1969688 | 0.9404062 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.49e-05 | 0 | TRUE | 0.6359976 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
