Two sample MR report
ADK_Epithelial against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0531714 | 0.8311734 | 0.9548115 |
| Weighted median | 4 | 0.0708209 | 0.0405312 | 0.0805822 |
| Inverse variance weighted | 4 | 0.0696154 | 0.0349641 | 0.0464752 |
| Simple mode | 4 | 0.0715737 | 0.0512196 | 0.2567103 |
| Weighted mode | 4 | 0.0715027 | 0.0529230 | 0.2695345 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0069582 | 2 | 0.9965270 |
| Inverse variance weighted | 0.0288201 | 3 | 0.9987099 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0586989 | 0.3969955 | 0.8960155 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.49e-05 | 0 | TRUE | 0.6358102 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
