Two sample MR report
AHDC1_Epithelial against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.5912724 | 1.1767876 | 0.7035882 |
| Weighted median | 3 | 0.0601389 | 0.0307443 | 0.0504532 |
| Inverse variance weighted | 3 | 0.0660506 | 0.0252007 | 0.0087676 |
| Simple mode | 3 | 0.0571673 | 0.0385671 | 0.2764757 |
| Weighted mode | 3 | 0.0554664 | 0.0357622 | 0.2610641 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.2128635 | 1 | 0.6445322 |
| Inverse variance weighted | 0.4121549 | 2 | 0.8137701 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.6133322 | 1.373889 | 0.7327003 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.5e-05 | 0 | TRUE | 0.6370432 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
