Two sample MR report
ARL16_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0252763 | 0.2083896 | 0.9231577 |
| Weighted median | 3 | 0.0316708 | 0.0171450 | 0.0647126 |
| Inverse variance weighted | 3 | 0.0357442 | 0.0145884 | 0.0142789 |
| Simple mode | 3 | 0.0314814 | 0.0215500 | 0.2815164 |
| Weighted mode | 3 | 0.0313950 | 0.0205231 | 0.2657105 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1698062 | 1 | 0.6802841 |
| Inverse variance weighted | 0.2559714 | 2 | 0.8798660 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.04454 | 0.1517345 | 0.818233 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.88e-05 | 0 | TRUE | 0.5551687 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
