Two sample MR report
ARL16_Macrophages against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | -0.0582185 | 0.1623743 | 0.7305052 |
| Weighted median | 9 | -0.0679796 | 0.0218232 | 0.0018394 |
| Inverse variance weighted | 9 | -0.0655619 | 0.0174786 | 0.0001761 |
| Simple mode | 9 | -0.0765514 | 0.0314657 | 0.0410194 |
| Weighted mode | 9 | -0.0762001 | 0.0341874 | 0.0563944 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.8103479 | 7 | 0.9973369 |
| Inverse variance weighted | 0.8124172 | 8 | 0.9991785 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0058993 | 0.1296829 | 0.9649874 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001808 | 0 | TRUE | 0.2020017 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
