Two sample MR report
ATPIF1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.2252866 | 0.4578786 | 0.6484836 |
| Weighted median | 6 | -0.1096347 | 0.0439916 | 0.0126963 |
| Inverse variance weighted | 6 | -0.1076483 | 0.0350340 | 0.0021215 |
| Simple mode | 6 | -0.1359728 | 0.0543094 | 0.0542463 |
| Weighted mode | 6 | -0.1331964 | 0.0593433 | 0.0747904 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.2795924 | 4 | 0.9910932 |
| Inverse variance weighted | 0.8114165 | 5 | 0.9762995 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1074182 | 0.1472969 | 0.506248 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.03e-05 | 0 | TRUE | 0.5018487 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
