Two sample MR report
BAIAP3_Epithelial against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.5833526 | 0.2944181 | 0.1418677 |
| Weighted median | 5 | -0.1521484 | 0.0671214 | 0.0234046 |
| Inverse variance weighted | 5 | -0.1638985 | 0.0517305 | 0.0015332 |
| Simple mode | 5 | -0.2306029 | 0.0990846 | 0.0804869 |
| Weighted mode | 5 | -0.0905236 | 0.0988579 | 0.4116371 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.7924349 | 3 | 0.8512756 |
| Inverse variance weighted | 2.8868304 | 4 | 0.5769392 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.2431182 | 0.1679918 | 0.2436465 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.46e-05 | 0 | TRUE | 0.579526 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
