Two sample MR report
C11orf24_Macrophages against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.6380695 | 1.7925983 | 0.7822998 |
| Weighted median | 3 | -0.0855317 | 0.0582806 | 0.1422168 |
| Inverse variance weighted | 3 | -0.0983562 | 0.0470402 | 0.0365374 |
| Simple mode | 3 | -0.0850814 | 0.0655858 | 0.3240231 |
| Weighted mode | 3 | -0.0850814 | 0.0674140 | 0.3341651 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0112640 | 1 | 0.9154778 |
| Inverse variance weighted | 0.1801489 | 2 | 0.9138631 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.3098136 | 0.7538846 | 0.7517721 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.18e-05 | 0 | TRUE | 0.6578191 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
