Two sample MR report
C19orf60_Macrophages against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0365672 | 0.1053910 | 0.7515286 |
| Weighted median | 5 | 0.0292228 | 0.0142319 | 0.0400400 |
| Inverse variance weighted | 5 | 0.0286933 | 0.0121661 | 0.0183506 |
| Simple mode | 5 | 0.0300632 | 0.0194775 | 0.1975886 |
| Weighted mode | 5 | 0.0302011 | 0.0177632 | 0.1643149 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0712921 | 3 | 0.9950442 |
| Inverse variance weighted | 0.0769492 | 4 | 0.9992786 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0036157 | 0.0480721 | 0.9447793 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001146 | 0 | TRUE | 0.3087455 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
