Two sample MR report
C20orf96_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 14 | -0.0197612 | 0.0442340 | 0.6630175 |
| Weighted median | 14 | -0.0170051 | 0.0075033 | 0.0234305 |
| Inverse variance weighted | 14 | -0.0114502 | 0.0056725 | 0.0435346 |
| Simple mode | 14 | -0.0184695 | 0.0118585 | 0.1433558 |
| Weighted mode | 14 | -0.0184695 | 0.0123262 | 0.1579167 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 5.246375 | 12 | 0.9492394 |
| Inverse variance weighted | 5.282267 | 13 | 0.9684424 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0048671 | 0.0256903 | 0.852906 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004208 | 0 | TRUE | 0.0509222 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
