Two sample MR report
CAT_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | -0.0627017 | 0.0745754 | 0.4388163 |
| Weighted median | 7 | 0.0179096 | 0.0108106 | 0.0975861 |
| Inverse variance weighted | 7 | 0.0210902 | 0.0080976 | 0.0092007 |
| Simple mode | 7 | 0.0236250 | 0.0173613 | 0.2224749 |
| Weighted mode | 7 | 0.0167033 | 0.0159139 | 0.3343266 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 4.435015 | 5 | 0.4886250 |
| Inverse variance weighted | 5.712520 | 6 | 0.4561516 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0509192 | 0.0450506 | 0.3096483 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002457 | 0 | TRUE | 0.1366004 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
