Two sample MR report
CBWD1_Macrophages against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 19 | -0.1103903 | 0.0540543 | 0.0569592 |
| Weighted median | 19 | -0.0924445 | 0.0156902 | 0.0000000 |
| Inverse variance weighted | 19 | -0.0886046 | 0.0113767 | 0.0000000 |
| Simple mode | 19 | -0.1029411 | 0.0244275 | 0.0005216 |
| Weighted mode | 19 | -0.0966456 | 0.0223856 | 0.0004149 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 13.94102 | 17 | 0.6712724 |
| Inverse variance weighted | 14.11098 | 18 | 0.7218282 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0145996 | 0.035413 | 0.6852957 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0014304 | 1e-07 | TRUE | 0.0003413 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
