Two sample MR report
CD84_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.1087295 | 0.0969450 | 0.3437260 |
| Weighted median | 5 | 0.0161430 | 0.0138599 | 0.2441293 |
| Inverse variance weighted | 5 | 0.0231811 | 0.0112241 | 0.0388959 |
| Simple mode | 5 | 0.0195648 | 0.0177600 | 0.3324575 |
| Weighted mode | 5 | 0.0168461 | 0.0166792 | 0.3696263 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1925833 | 3 | 0.9787776 |
| Inverse variance weighted | 0.9818694 | 4 | 0.9125326 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0842505 | 0.094832 | 0.4397587 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6.71e-05 | 0 | TRUE | 0.4366982 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
