Two sample MR report
CDH26_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.0578958 | 0.0751717 | 0.5217264 |
| Weighted median | 4 | 0.0258907 | 0.0155455 | 0.0958164 |
| Inverse variance weighted | 4 | 0.0269741 | 0.0133290 | 0.0429993 |
| Simple mode | 4 | 0.0266769 | 0.0208108 | 0.2899727 |
| Weighted mode | 4 | 0.0264936 | 0.0181975 | 0.2414423 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.4916844 | 2 | 0.7820456 |
| Inverse variance weighted | 0.6663839 | 3 | 0.8810808 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0310704 | 0.0743364 | 0.7165697 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.73e-05 | 0 | TRUE | 0.5139476 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
