Two sample MR report
CECR1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0249709 | 0.1514446 | 0.8795189 |
| Weighted median | 5 | -0.0369951 | 0.0152591 | 0.0153310 |
| Inverse variance weighted | 5 | -0.0404258 | 0.0128651 | 0.0016764 |
| Simple mode | 5 | -0.0371974 | 0.0202858 | 0.1406282 |
| Weighted mode | 5 | -0.0371102 | 0.0187522 | 0.1189409 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.4791575 | 3 | 0.9234460 |
| Inverse variance weighted | 0.6669807 | 4 | 0.9553376 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0503526 | 0.1161841 | 0.6940059 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003715 | 0 | TRUE | 0.0673641 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
