Two sample MR report


CLEC10A_Epithelial against bbj-a-88

Date: 13 January, 2026


Results from two sample MR:

method nsnp b se pval
Weighted median 3 -0.0366401 0.0135193 0.0067241
Inverse variance weighted 3 -0.0374872 0.0111994 0.0008162
Simple mode 3 -0.0358443 0.0159066 0.1529872
Weighted mode 3 -0.0358443 0.0150415 0.1400322

Heterogeneity tests

method Q Q_df Q_pval
Inverse variance weighted 0.0533461 2 0.9736795

Test for directional horizontal pleiotropy

egger_intercept se pval
NA NA NA

Test that the exposure is upstream of the outcome

snp_r2.exposure snp_r2.outcome correct_causal_direction steiger_pval
4.17e-05 0 TRUE 0.542045

Note - R^2 values are approximate


Forest plot of single SNP MR

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Comparison of results using different MR methods

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Funnel plot

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Leave-one-out sensitivity analysis

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