Two sample MR report
CNKSR1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.0080020 | 0.1608816 | 0.9627152 |
| Weighted median | 6 | -0.0536887 | 0.0185256 | 0.0037545 |
| Inverse variance weighted | 6 | -0.0539779 | 0.0151221 | 0.0003577 |
| Simple mode | 6 | -0.0566133 | 0.0236838 | 0.0623586 |
| Weighted mode | 6 | -0.0522828 | 0.0212068 | 0.0568516 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1691618 | 4 | 0.9966185 |
| Inverse variance weighted | 0.3189037 | 5 | 0.9972724 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0331919 | 0.0857748 | 0.718488 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001172 | 0 | TRUE | 0.3053281 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
