Two sample MR report
CPNE1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | -0.1313264 | 0.0968580 | 0.2172544 |
| Weighted median | 9 | -0.0854283 | 0.0174159 | 0.0000009 |
| Inverse variance weighted | 9 | -0.0826840 | 0.0124366 | 0.0000000 |
| Simple mode | 9 | -0.0875374 | 0.0238244 | 0.0062706 |
| Weighted mode | 9 | -0.0870362 | 0.0235798 | 0.0061202 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.5419741 | 7 | 0.9992778 |
| Inverse variance weighted | 0.7984099 | 8 | 0.9992294 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0390047 | 0.0770243 | 0.6281356 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 7.4e-05 | 0 | TRUE | 0.4211135 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
