Two sample MR report
CTD-2270L9.4_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0506011 | 0.2475228 | 0.8716245 |
| Weighted median | 3 | -0.0550370 | 0.0193624 | 0.0044766 |
| Inverse variance weighted | 3 | -0.0578511 | 0.0146722 | 0.0000805 |
| Simple mode | 3 | -0.0539140 | 0.0224847 | 0.1386527 |
| Weighted mode | 3 | -0.0537732 | 0.0220261 | 0.1346980 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0045014 | 1 | 0.9465079 |
| Inverse variance weighted | 0.1971543 | 2 | 0.9061258 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0750413 | 0.1709671 | 0.7366917 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.68e-05 | 0 | TRUE | 0.5705858 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
