Two sample MR report
CYGB_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | 0.0210738 | 0.0369117 | 0.5887791 |
| Weighted median | 8 | 0.0113088 | 0.0070152 | 0.1069527 |
| Inverse variance weighted | 8 | 0.0132850 | 0.0057703 | 0.0213184 |
| Simple mode | 8 | 0.0104566 | 0.0102716 | 0.3425601 |
| Weighted mode | 8 | 0.0105720 | 0.0096408 | 0.3091045 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.6162280 | 6 | 0.9961238 |
| Inverse variance weighted | 0.6618696 | 7 | 0.9986119 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0073834 | 0.0345603 | 0.8379033 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002175 | 0 | TRUE | 0.1605953 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
