Two sample MR report
CYP4B1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | 0.0374711 | 0.0588126 | 0.5475674 |
| Weighted median | 8 | 0.0261552 | 0.0141748 | 0.0650095 |
| Inverse variance weighted | 8 | 0.0257584 | 0.0112297 | 0.0218032 |
| Simple mode | 8 | 0.0267252 | 0.0183496 | 0.1886119 |
| Weighted mode | 8 | 0.0269144 | 0.0180579 | 0.1797251 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0750688 | 6 | 0.9999914 |
| Inverse variance weighted | 0.1162307 | 7 | 0.9999961 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0064591 | 0.0318362 | 0.8459309 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001246 | 0 | TRUE | 0.2882546 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
