Two sample MR report
DAW1_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.1204727 | 0.1680297 | 0.5478155 |
| Weighted median | 4 | -0.0368807 | 0.0131734 | 0.0051161 |
| Inverse variance weighted | 4 | -0.0381231 | 0.0112442 | 0.0006977 |
| Simple mode | 4 | -0.0351822 | 0.0174796 | 0.1376155 |
| Weighted mode | 4 | -0.0359102 | 0.0172720 | 0.1291131 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.3357326 | 2 | 0.8454669 |
| Inverse variance weighted | 0.5770009 | 3 | 0.9016767 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0444215 | 0.0904364 | 0.6719023 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.76e-05 | 0 | TRUE | 0.4734257 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
