Two sample MR report
DAW1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.0907173 | 0.2239077 | 0.7125241 |
| Weighted median | 5 | 0.0321940 | 0.0168838 | 0.0565473 |
| Inverse variance weighted | 5 | 0.0317835 | 0.0135585 | 0.0190694 |
| Simple mode | 5 | 0.0336512 | 0.0211534 | 0.1868599 |
| Weighted mode | 5 | 0.0265741 | 0.0208387 | 0.2712594 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0556343 | 3 | 0.9965676 |
| Inverse variance weighted | 0.3560591 | 4 | 0.9859138 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0660096 | 0.1204313 | 0.621767 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 7e-05 | 0 | TRUE | 0.4265576 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
