Two sample MR report
DIMT1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.2022295 | 0.2321124 | 0.5437307 |
| Weighted median | 3 | 0.0497255 | 0.0286948 | 0.0831111 |
| Inverse variance weighted | 3 | 0.0477353 | 0.0241376 | 0.0479698 |
| Simple mode | 3 | 0.0740361 | 0.0392165 | 0.1996551 |
| Weighted mode | 3 | 0.0695599 | 0.0408261 | 0.2305305 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.6967202 | 1 | 0.4038879 |
| Inverse variance weighted | 1.8691402 | 2 | 0.3927547 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.1583409 | 0.1462351 | 0.4747099 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.08e-05 | 0 | TRUE | 0.5997185 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
