Two sample MR report
DNAJB13_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 20 | -0.0033582 | 0.0318639 | 0.9172303 |
| Weighted median | 20 | -0.0235084 | 0.0088709 | 0.0080478 |
| Inverse variance weighted | 20 | -0.0219961 | 0.0064773 | 0.0006842 |
| Simple mode | 20 | -0.0180868 | 0.0154211 | 0.2553460 |
| Weighted mode | 20 | -0.0278625 | 0.0149271 | 0.0774733 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 13.37584 | 18 | 0.7687794 |
| Inverse variance weighted | 13.73272 | 19 | 0.7990435 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0123337 | 0.0206459 | 0.5576854 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005067 | 0 | TRUE | 0.0324735 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
