Two sample MR report
DYDC2_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 10 | 0.0224578 | 0.0815101 | 0.7898984 |
| Weighted median | 10 | -0.0437784 | 0.0099089 | 0.0000100 |
| Inverse variance weighted | 10 | -0.0476336 | 0.0074726 | 0.0000000 |
| Simple mode | 10 | -0.0437123 | 0.0138445 | 0.0115991 |
| Weighted mode | 10 | -0.0437123 | 0.0140755 | 0.0126089 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.105607 | 8 | 0.9974891 |
| Inverse variance weighted | 1.851321 | 9 | 0.9936064 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.035343 | 0.0409278 | 0.4129765 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002295 | 0 | TRUE | 0.1534142 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
