Two sample MR report
DYDC2_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 12 | 0.0274742 | 0.1232970 | 0.8281536 |
| Weighted median | 12 | 0.0473862 | 0.0151619 | 0.0017760 |
| Inverse variance weighted | 12 | 0.0514873 | 0.0117296 | 0.0000114 |
| Simple mode | 12 | 0.0469188 | 0.0206720 | 0.0443324 |
| Weighted mode | 12 | 0.0466888 | 0.0200261 | 0.0397714 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.390637 | 10 | 0.9923754 |
| Inverse variance weighted | 2.428914 | 11 | 0.9963311 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0124177 | 0.0634706 | 0.8488063 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003296 | 0 | TRUE | 0.0849536 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
