Two sample MR report
ELP5_Macrophages against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 13 | 0.0705071 | 0.0831678 | 0.4146326 |
| Weighted median | 13 | -0.0653392 | 0.0145212 | 0.0000068 |
| Inverse variance weighted | 13 | -0.0817913 | 0.0111856 | 0.0000000 |
| Simple mode | 13 | -0.0670753 | 0.0232402 | 0.0136728 |
| Weighted mode | 13 | -0.0653784 | 0.0196018 | 0.0059393 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 6.651805 | 11 | 0.8265396 |
| Inverse variance weighted | 10.066938 | 12 | 0.6100881 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1251568 | 0.0677253 | 0.091644 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0010694 | 1e-07 | TRUE | 0.0019821 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
