Two sample MR report
ENOSF1_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 14 | -0.0549033 | 0.1446032 | 0.7108153 |
| Weighted median | 14 | 0.0551807 | 0.0135939 | 0.0000492 |
| Inverse variance weighted | 14 | 0.0588654 | 0.0104985 | 0.0000000 |
| Simple mode | 14 | 0.0618645 | 0.0216805 | 0.0135667 |
| Weighted mode | 14 | 0.0527867 | 0.0210551 | 0.0262362 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.978578 | 12 | 0.9956934 |
| Inverse variance weighted | 3.600857 | 13 | 0.9947438 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0493749 | 0.0625913 | 0.4455075 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002177 | 0 | TRUE | 0.1640621 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
