Two sample MR report
ERP27_Epithelial against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 21 | -0.0047021 | 0.0152583 | 0.7613074 |
| Weighted median | 21 | 0.0111385 | 0.0053900 | 0.0387782 |
| Inverse variance weighted | 21 | 0.0100700 | 0.0040936 | 0.0138955 |
| Simple mode | 21 | 0.0194944 | 0.0092064 | 0.0469438 |
| Weighted mode | 21 | 0.0119590 | 0.0084568 | 0.1727032 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 8.032739 | 19 | 0.9863384 |
| Inverse variance weighted | 9.042717 | 20 | 0.9824072 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0101767 | 0.0101263 | 0.3275362 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0013148 | 0 | TRUE | 0.0005522 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
