Two sample MR report
ERP27_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 18 | -0.0245835 | 0.0335497 | 0.4743112 |
| Weighted median | 18 | -0.0265591 | 0.0126022 | 0.0350748 |
| Inverse variance weighted | 18 | -0.0266872 | 0.0090003 | 0.0030252 |
| Simple mode | 18 | -0.0372956 | 0.0186854 | 0.0622124 |
| Weighted mode | 18 | -0.0292968 | 0.0146919 | 0.0624365 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 11.18897 | 16 | 0.7976735 |
| Inverse variance weighted | 11.19321 | 17 | 0.8463455 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0014057 | 0.0215953 | 0.9489065 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0012633 | 0 | TRUE | 0.0007179 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
