Two sample MR report
ETFB_Epithelial against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -1.4583992 | 1.7036437 | 0.5492769 |
| Weighted median | 3 | 0.0786002 | 0.0370870 | 0.0340613 |
| Inverse variance weighted | 3 | 0.0669727 | 0.0298970 | 0.0250835 |
| Simple mode | 3 | 0.0898249 | 0.0440300 | 0.1781564 |
| Weighted mode | 3 | 0.0898249 | 0.0463411 | 0.1921592 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.1012193 | 1 | 0.7503713 |
| Inverse variance weighted | 0.9031331 | 2 | 0.6366300 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.553402 | 0.6179835 | 0.535063 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 1.85e-05 | 0 | TRUE | 0.6844011 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
