Two sample MR report
FAM3B_Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.1146755 | 0.1194353 | 0.5129415 |
| Weighted median | 3 | -0.0468015 | 0.0208917 | 0.0250780 |
| Inverse variance weighted | 3 | -0.0417448 | 0.0168253 | 0.0130985 |
| Simple mode | 3 | -0.0510132 | 0.0240869 | 0.1683654 |
| Weighted mode | 3 | -0.0510132 | 0.0239265 | 0.1666580 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.9647299 | 1 | 0.3259981 |
| Inverse variance weighted | 1.3451476 | 2 | 0.5103932 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.072725 | 0.1179108 | 0.6481616 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.63e-05 | 0 | TRUE | 0.4777767 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
